esbuild-register

Install

yarn add esm esbuild-register --dev

You need esm as well because esbuild doesn't compile import and export statements to commonjs require.

esbuild is also required as a peer dependency.

node -r esm -r esbuild-register file.ts

It will use jsxFactory, jsxFragmentFactory and target options from your tsconfig.json

When using Yarn, you can add an npm script:

"ts": "node -r esm -r esbuild-register"

to shorten the command, now just run yarn ts file.ts instead.